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                            Original Research
                            
                            
                            6. 
                            
                            Risk analysis and exposure assessment of ochratoxin 
                            A in Serbia - 
                            
                            Dragan R. Milicevic, Srdan Stefanovic, Sasa Jankovic, 
                            Tatjana Radicevic
                            Vet World. 2012; 5(7): 412-416
              
               
              
              doi: 
              10.5455/vetworld.2012.412-416
              
              
               
              
              
              
   
 
              
               
               
               
              
              
              Abstract
              
              
                            Aim: 
                            The aim of this study was to check the current 
                            status of OTA contamination of the Serbian pork and 
                            chicken meat in naturally exposed animals which are 
                            part of chain production. The knowledge of these 
                            factors, their importance and significance, can be 
                            used as a tool from the food safety point of view to 
                            predict if OTA content in pork and chicken tissues 
                            poses a risk to human health and deleterious effects 
                            on animals' health and well-being. 
              
                             Materials and 
                            Methods: A total of 540 samples of pigs blood, 
                            kidney, liver and chicken gizzard were randomly 
                            selected from slaughtered pigs (n=90) and chicken 
                            (n=90) and analyzed for the presence of ochratoxin A 
                            (OTA) by High-performance liquid chromatography (HPLC-FL). 
              
                            
                            Results: In porcine tissue samples, of the 90 
                            liver samples, 26.6% contained OTA in the range of 
                            0.22-14.5 ng/g. The incidence of OTA in serum and 
                            kidneys were very similar (31% and 33.3%, 
                            respectively), with a maximum concentration of 220.8 
                            ng/mL, and 52.5 ng/g, respectively. Majority of 
                            chickens' tissues samples, were not found to contain 
                            measurable amounts of OTA. Moreover, the OTA levels 
                            found in analysed tissues were low in general. 
              
                             
                            Conclusion: The results of this preliminary 
                            research indicate that the content of OTA in the 
                            examined tissues are far below the values that 
                            represent hazard to the health of consumers. 
                            However, the results of this study show that in 
                            Serbia, consumers are nevertheless frequently 
                            exposed to ochratoxins. 
              
                             Key words: ochratoxin 
                            A, tissues samples, residue, exposure assessment